Cameron McIntyre, Ph.D., Co-Founder – Dr. McIntyre received his Ph.D. in Biomedical Engineering from Case Western Reserve University in 2001, where his doctoral research focused on the biophysics of the interaction between extracellular electric fields and neurons. From 2001 to 2003, Dr. McIntyre performed post-doctoral training at Johns Hopkins University and Emory University where he studied deep brain stimulation (DBS). In 2003 he joined the faculty at the Cleveland Clinic Foundation where he is currently appointed as Associate Staff in the Department of Biomedical Engineering and holds adjunct professorships at Case Western Reserve University. 

Over the last five years the McIntyre lab has published extensively and developed international prominence by coupling theoretical and experimental analyses of DBS. Numerous research grants from the American Parkinson Disease Association, the W.H. Coulter Foundation, and the National Institutes of Health have supported his research program that focuses on both the neurophysiological effects and engineering design of DBS systems.  The fundamental goal of his research program is to use growing knowledge on the therapeutic mechanisms of DBS to better engineer the next generation of DBS devices.

Jaimie Henderson, M.D., – Dr. Henderson received his B.A degree at Washington University, St. Louis, Biology in 1984, M.D. at Rush Medical College in 1988, Medical Education and Internship at Rush University Medical College, IL in 1988 and 1989 respectively, and completed his residency at St. Louis University Hospital, MO in 1995. Dr. Henderson received his Board Certification in Neurological Surgery at the American Board of Neurological Surgery in 2000. His clinical focus is in Neurological Surgery and Neurosurgery. Dr. Henderson received his administrative appointment at Stanford University Medicine as Director, Stereotactic and Functional Neurosurgery in 2004, where he is currently serving. He has Graduate and Fellowship Program Affiliations in Neurosurgery. Dr. Henderson conducted Clinical Trials in Safety and Efficacy Study of GAD Gene Transfer Therapy in Parkinson’s disease, (no longer recruiting.) His current research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; deformable patient-specific atlases for targeting brain structures; cortical physiology and its relationship to normal and pathological movement; neural prostheses; and the development of novel neuromodulatory techniques for the treatment of movement disorders, pain, and other neurological diseases.

Andre Machado, M.D., Ph.D., Co-Founder – Dr. Machado earned his medical degree and PhD in Neuroscience at the University of Sao Paulo Medical school and then completed Neurosurgery training at the U. of Sao Paulo and the Cleveland Clinic. He completed two years of Fellowship training in Stereotactic and Functional Neurosurgery at the Cleveland Clinic Center for Neurological Restoration in 2006. During that same year, he won the Gildenberg Award in Stereotactic and Functional Neurosurgery by the Joint Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons. Dr. Machado’s research interests are in the fields of central nervous system plasticity and its implications in stroke rehabilitation, chronic pain and in movement disorders. In his lab at the Cleveland Clinic, Dr. Machado is the principal investigator on translational research studies aimed at the development of novel therapies for stroke rehabilitation, currently funded by a National Institutes of Health award. His clinical area of expertise is the neurosurgical management of patients with otherwise intractable pain syndromes and severe movement disorders such as Parkinson's disease, dystonia and spasticity.

Nicholas D. Schiff, M.D., Co-Founder – Dr. Schiff is Associate Professor of Neurology and Neuroscience at the Weill Medical College of Cornell University and Associate Attending Neurologist at the New York Presbyterian Hospital. He is Director of the Laboratory of Cognitive Neuromodulation at Weill-Cornell where he conducts investigative studies of the pathophysiology of impaired consciousness, the neurophysiological mechanisms of arousal regulation, and the effects of deep brain electrical stimulation techniques on forebrain integration.   A diplomat of the American Board of Psychiatry and Neurology, Dr. Schiff graduated with Departmental Honors and with Distinction from Stanford University and with Honors in Research from the Cornell University Medical College. He completed his residency in Neurology at the New York Hospital and served as the Administrative Chief Resident of the Neurology Department 1995-1996.

Dr. Schiff is an internationally recognized leader in the neurological subfield of disorders of consciousness and an established physician-scientist dedicated to translational research. His research program precisely bridges basic neuroscience and pre-commercial development of therapeutic devices and  medical diagnostics. Dr. Schiff's work is recognized as highly original and aimed at important and difficult problems:  identifying mechanisms of impaired cognitive function resulting from complex brain injuries and developing novel therapeutic strategies to treat acquired cognitive disabilities.

Dr. Schiff's research has been supported by grants from the NIH (NINDS, NIMH), private foundations (Charles A. Dana Foundation, James S. McDonnell Foundation) and industry (IntElect Medical, Inc). He has authored over 40 peer-reviewed scientific publications that span original work in clinical neuroimaging of disorders of consciousness, the fundamental neurophysiology of cortical and thalamic neurons, and advanced signal processing of neurophysiological data. He is also a listed inventor on several U.S. and international patents. His long-range goals are to develop therapeutic strategies and improved diagnostics for the rational therapy of chronic cognitive disabilities resulting from brain injuries.

P. Hunter Peckham, Ph.d. – Dr. Peckham received his undergraduate degree in mechanical engineering from Clarkson College of Technology (now Clarkson University), Potsdam, NY, and his MS and PhD degrees in biomedical engineering from Case Western Reserve University (CWRU), Cleveland, OH. He is currently: Donnell Institute Professor of Biomedical Engineering and Orthopaedics at CWRU; Senior Career Research Scientist, Department of Veterans Affairs; and Director, Orthopaedic Research, MetroHealth Medical Center.  

Dr. Peckham presently serves as the Director of the Functional Electrical Stimulation (FES) Center This research consortium was established with the Department of Veterans Affairs, Case Western Reserve University and MetroHealth Medical Center to broaden the clinical, educational, and technology base of activities related to restoring function for people with disabilities through the use of electrical activation of the nervous system.  The FES Center brings together, in a unique interdisciplinary environment, approximately 28 faculty, primarily from medicine and engineering, and approximately 105 staff including engineers, therapists, technicians and students.  The research programs are directed at functional restoration of upper and lower extremities, and bowel and bladder function in spinal cord injury and stroke.  As director, Dr. Peckham brings together a diverse group of researchers and clinicians to impact functional restoration to a severely impaired population, and as such his contributions are of immediate impact to individuals with physical disabilities.

Dr. Peckham is internationally known for his research in the utilization of functional electrical stimulation to restore hand/arm control to individuals of high-level spinal cord injury (quadriplegia).  The major area of Dr. Peckham's research is in rehabilitation engineering and neural prostheses.  He and his collaborators have developed implantable neural prostheses that utilize electrical stimulation to control neuromuscular activation.  They have implemented procedures to provide control of grasp-release in individuals with tetraplegia.  This function enables individuals who are disabled due to paralysis from central nervous system injury to regain the ability to perform essential activities of daily living.
 
Dr. Peckham’s present efforts concern the integration of technological rehabilitation and surgical approaches to restore functional capabilities. He is currently working on an advanced neuroprosthesis that employs implantable sensors for internal control and regulation of movement. 

Dr. Peckham’s publications include over 90 journal articles, 27 book chapters and 6 edited books and journals.  He is an editor for the upcoming Textbook of Neuromodulation. His work has been featured in numerous local and national television and radio broadcasts

Dr. Peckham is a member of the  NIH National Institute of Bioimaging and Bioengineering National Advisory Council and currently serves on the Advisory Boards of:  Kessler Medical Rehabilitation Research and Education Corporation; Shriners Hospital for Children; Advanced Cochlear Sciences (ACS); Deans Advisory Council, School of Arts and Sciences, Clarkson University; Advisory Committee on Neural Prosthetics and DBS, NIH/NINDS.  He is a fellow of the American Institute of Medical and Biological Engineering and a fellow and honorary member of the American Spinal Injury Association, and was elected to the National Academy of Engineering in 2002, one of the highest professional honors for an engineer.  He is a member of numerous professional organizations.